Cortical interaction of bilateral inputs is similar for noxious and innocuous stimuli but leads to different perceptual effects

The cerebral integration of somatosensory inputs from multiple sources is essential to produce adapted behaviors. Previous studies suggest that bilateral interact differently depending on stimulus characteristics, including their noxious nature. aim this study was clarify how evoked by laser stimuli, shocks, and innocuous shocks in terms perception brain responses. experiment comprised two conditions (right-hand stimulation concurrent both hands) which painful non-painful were delivered. Perception, somatosensory-evoked potentials (P45, N100, P260), laser-evoked (N1, N2 P2) event-related spectral perturbations (delta gamma oscillation power) compared between modalities. amplitude negative vertex (N2 or N100) the power delta/theta oscillations increased with unilateral condition, regardless type (P < 0.01). However, for 0.01), but not stimuli = 0.08). Despite similarities activity, interacted remained unchanged, increased. This may reflect a ceiling effect attentional capture warrants further investigations examine regulation such interactions bottom–up top–down processes.